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Potential Contribution of Exosomes to the Prion-Like Propagation of Lesions in Alzheimer’s Disease

Since the discovery of prion diseases, the concept has emerged that a protein could be a transmissible pathogen. As such, this transmissible pathogen agent can transfer its pathological mis-folded shape to the same but normally folded protein thus leading to the propagation of a disease. This idea i...

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Detalles Bibliográficos
Autores principales: Vingtdeux, Valérie, Sergeant, Nicolas, Buée, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389776/
https://www.ncbi.nlm.nih.gov/pubmed/22783199
http://dx.doi.org/10.3389/fphys.2012.00229