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Potential Contribution of Exosomes to the Prion-Like Propagation of Lesions in Alzheimer’s Disease
Since the discovery of prion diseases, the concept has emerged that a protein could be a transmissible pathogen. As such, this transmissible pathogen agent can transfer its pathological mis-folded shape to the same but normally folded protein thus leading to the propagation of a disease. This idea i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389776/ https://www.ncbi.nlm.nih.gov/pubmed/22783199 http://dx.doi.org/10.3389/fphys.2012.00229 |