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Genetic Evidence Links the ASTRA Protein Chaperone Component Tti2 to the SAGA Transcription Factor Tra1

Tra1 is a 3744-residue component of the Saccharomyces cerevisiae SAGA, NuA4, and ASTRA complexes. Tra1 contains essential C-terminal PI3K and FATC domains, but unlike other PIKK (phosphoinositide three-kinase–related kinase) family members, lacks kinase activity. To analyze functions of the FATC dom...

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Detalles Bibliográficos
Autores principales: Genereaux, Julie, Kvas, Stephanie, Dobransky, Dominik, Karagiannis, Jim, Gloor, Gregory B., Brandl, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389973/
https://www.ncbi.nlm.nih.gov/pubmed/22505622
http://dx.doi.org/10.1534/genetics.112.140459