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Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

How microgravitational space environments affect aging is not well understood. We observed that, in Caenorhabditis elegans, spaceflight suppressed the formation of transgenically expressed polyglutamine aggregates, which normally accumulate with increasing age. Moreover, the inactivation of each of...

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Detalles Bibliográficos
Autores principales: Honda, Yoko, Higashibata, Akira, Matsunaga, Yohei, Yonezawa, Yukiko, Kawano, Tsuyoshi, Higashitani, Atsushi, Kuriyama, Kana, Shimazu, Toru, Tanaka, Masashi, Szewczyk, Nathaniel J., Ishioka, Noriaki, Honda, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390002/
https://www.ncbi.nlm.nih.gov/pubmed/22768380
http://dx.doi.org/10.1038/srep00487