Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice

Mutations in the parkin gene are currently thought to be the most common cause of recessive familial Parkinsonism. Parkin functions as an E3 ligase to regulate protein turnover, and its function in mitochondrial quality control has been reported recently. Overexpression of parkin has been found to p...

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Detalles Bibliográficos
Autores principales: Bian, Minjuan, Liu, Jie, Hong, Xiaoqi, Yu, Mei, Huang, Yufang, Sheng, Zhejin, Fei, Jian, Huang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390003/
https://www.ncbi.nlm.nih.gov/pubmed/22792139
http://dx.doi.org/10.1371/journal.pone.0039953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390003/
https://www.ncbi.nlm.nih.gov/pubmed/22792139
http://dx.doi.org/10.1371/journal.pone.0039953

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