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Novel pharmacological strategies to prevent aortic complications in Marfan syndrome

The Marfan syndrome (MFS) is a systemic connective tissue disorder caused by mutations in the FBN1 gene. Recent molecular studies, most performed in mouse models, revealed that the MFS is more a developmental abnormality with broad and complex effects on the morphogenesis and function of multiple or...

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Detalles Bibliográficos
Autores principales: Matt, Peter, Eckstein, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390093/
https://www.ncbi.nlm.nih.gov/pubmed/22783312
http://dx.doi.org/10.3724/SP.J.1263.2011.00254