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Novel pharmacological strategies to prevent aortic complications in Marfan syndrome
The Marfan syndrome (MFS) is a systemic connective tissue disorder caused by mutations in the FBN1 gene. Recent molecular studies, most performed in mouse models, revealed that the MFS is more a developmental abnormality with broad and complex effects on the morphogenesis and function of multiple or...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390093/ https://www.ncbi.nlm.nih.gov/pubmed/22783312 http://dx.doi.org/10.3724/SP.J.1263.2011.00254 |