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Improved Production of Tryptophan in Genetically Engineered Escherichia coli with TktA and PpsA Overexpression

Intracellular precursor supply is a critical factor for amino acid productivity. In the present study, ppsA and tktA genes were overexpressed in genetically engineered Escherichia coli to enhance the availability of two precursor substrates, phosphoenolpyruvate and erythrose-4-phosphate. The enginee...

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Detalles Bibliográficos
Autores principales: Shen, Tong, Liu, Qing, Xie, Xixian, Xu, Qingyang, Chen, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390157/
https://www.ncbi.nlm.nih.gov/pubmed/22791961
http://dx.doi.org/10.1155/2012/605219