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Improved Production of Tryptophan in Genetically Engineered Escherichia coli with TktA and PpsA Overexpression
Intracellular precursor supply is a critical factor for amino acid productivity. In the present study, ppsA and tktA genes were overexpressed in genetically engineered Escherichia coli to enhance the availability of two precursor substrates, phosphoenolpyruvate and erythrose-4-phosphate. The enginee...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390157/ https://www.ncbi.nlm.nih.gov/pubmed/22791961 http://dx.doi.org/10.1155/2012/605219 |