Quantitative Analysis of Survivin Protein Expression and Its Therapeutic Depletion by an Antisense Oligonucleotide in Human Lung Tumors

RNA-directed antisense and interference therapeutics are a promising treatment option for cancer. The demonstration of depletion of target proteins within human tumors in vivo using validated methodology will be a key to the application of this technology. Here, we present a flow cytometric-based ap...

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Detalles Bibliográficos
Autores principales: Olsen, Anna L, Davies, Joanne M, Medley, Louise, Breen, David, Talbot, Denis C, McHugh, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390226/
https://www.ncbi.nlm.nih.gov/pubmed/23344082
http://dx.doi.org/10.1038/mtna.2012.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390226/
https://www.ncbi.nlm.nih.gov/pubmed/23344082
http://dx.doi.org/10.1038/mtna.2012.19

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