Small RNA-Mediated Epigenetic Myostatin Silencing

Myostatin (Mstn) is a secreted growth factor that negatively regulates muscle mass and is therefore a potential pharmacological target for the treatment of muscle wasting disorders such as Duchenne muscular dystrophy. Here we describe a novel Mstn blockade approach in which small interfering RNAs (s...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts, Thomas C, Andaloussi, Samir EL, Morris, Kevin V, McClorey, Graham, Wood, Matthew JA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390243/
https://www.ncbi.nlm.nih.gov/pubmed/23344003
http://dx.doi.org/10.1038/mtna.2012.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390243/
https://www.ncbi.nlm.nih.gov/pubmed/23344003
http://dx.doi.org/10.1038/mtna.2012.15

Ejemplares similares