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An RNA Alternative to Human Transferrin: A New Tool for Targeting Human Cells

The transferrin receptor, CD71, is an attractive target for drug development because of its high expression on a number of cancer cell lines and the blood brain barrier. To generate serum-stabilized aptamers that recognize the human transferrin receptor, we have modified the traditional aptamer sele...

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Detalles Bibliográficos
Autores principales: Wilner, Samantha E, Wengerter, Brian, Maier, Keith, de Lourdes Borba Magalhães, Maria, Del Amo, David Soriano, Pai, Supriya, Opazo, Felipe, Rizzoli, Silvio O, Yan, Amy, Levy, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390244/
https://www.ncbi.nlm.nih.gov/pubmed/23344001
http://dx.doi.org/10.1038/mtna.2012.14