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An RNA Alternative to Human Transferrin: A New Tool for Targeting Human Cells
The transferrin receptor, CD71, is an attractive target for drug development because of its high expression on a number of cancer cell lines and the blood brain barrier. To generate serum-stabilized aptamers that recognize the human transferrin receptor, we have modified the traditional aptamer sele...
Autores principales: | Wilner, Samantha E, Wengerter, Brian, Maier, Keith, de Lourdes Borba Magalhães, Maria, Del Amo, David Soriano, Pai, Supriya, Opazo, Felipe, Rizzoli, Silvio O, Yan, Amy, Levy, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390244/ https://www.ncbi.nlm.nih.gov/pubmed/23344001 http://dx.doi.org/10.1038/mtna.2012.14 |
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