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The CXCR3(+)CD56Bright Phenotype Characterizes a Distinct NK Cell Subset with Anti-Fibrotic Potential That Shows Dys-Regulated Activity in Hepatitis C

BACKGROUND: In mouse models, natural killer (NK) cells have been shown to exert anti-fibrotic activity via killing of activated hepatic stellate cells (HSC). Chemokines and chemokine receptors critically modulate hepatic recruitment of NK cells. In hepatitis C, the chemokine receptor CXCR3 and its l...

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Detalles Bibliográficos
Autores principales: Eisenhardt, Marianne, Glässner, Andreas, Krämer, Benjamin, Körner, Christian, Sibbing, Bernhard, Kokordelis, Pavlos, Nischalke, Hans Dieter, Sauerbruch, Tilman, Spengler, Ulrich, Nattermann, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390318/
https://www.ncbi.nlm.nih.gov/pubmed/22792160
http://dx.doi.org/10.1371/journal.pone.0038846