Hypoxia Changes the Expression of the Epidermal Growth Factor (EGF) System in Human Hearts and Cultured Cardiomyocytes

BACKGROUND: The epidermal growth factor (EGF) receptors HER2 and HER4 and the ligands HB-EGF and NRG1 are crucial for heart development. The purpose of our study was to investigate the role of the complete EGF system in relation to hypoxia of the heart. METHODOLOGY/PRINCIPAL FINDINGS: We examined th...

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Detalles Bibliográficos
Autores principales: Munk, Mathias, Memon, Ashfaque Ahmed, Goetze, Jens Peter, Nielsen, Lars Bo, Nexo, Ebba, Sorensen, Boe Sandahl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390334/
https://www.ncbi.nlm.nih.gov/pubmed/22792252
http://dx.doi.org/10.1371/journal.pone.0040243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390334/
https://www.ncbi.nlm.nih.gov/pubmed/22792252
http://dx.doi.org/10.1371/journal.pone.0040243

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