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DNA Methyltransferases Are Required to Induce Heterochromatic Re-Replication in Arabidopsis

The relationship between epigenetic marks on chromatin and the regulation of DNA replication is poorly understood. Mutations of the H3K27 methyltransferase genes, ARABIDOPSIS TRITHORAX-RELATED PROTEIN5 (ATXR5) and ATXR6, result in re-replication (repeated origin firing within the same cell cycle). H...

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Detalles Bibliográficos
Autores principales: Stroud, Hume, Hale, Christopher J., Feng, Suhua, Caro, Elena, Jacob, Yannick, Michaels, Scott D., Jacobsen, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390372/
https://www.ncbi.nlm.nih.gov/pubmed/22792077
http://dx.doi.org/10.1371/journal.pgen.1002808