Cargando…

The Role of Dlc1 Isoform 2 in K-Ras2(G12D) Induced Thymic Cancer

The Deleted in liver cancer one (Dlc1) tumor suppressor gene encodes a RhoGTPase activating protein (RhoGAP). The Dlc1 gene has multiple transcriptional isoforms and we have previously established a mouse strain containing a gene trap (gt) insertion, which specifically reduces the expression of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Sabbir, Mohammad Golam, Prieditis, Heather, Ravinsky, Esther, Mowat, Michael R. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390377/
https://www.ncbi.nlm.nih.gov/pubmed/22792269
http://dx.doi.org/10.1371/journal.pone.0040302