Antiviral Activity of a Small Molecule Deubiquitinase Inhibitor Occurs via Induction of the Unfolded Protein Response

Ubiquitin (Ub) is a vital regulatory component in various cellular processes, including cellular responses to viral infection. As obligate intracellular pathogens, viruses have the capacity to manipulate the ubiquitin (Ub) cycle to their advantage by encoding Ub-modifying proteins including deubiqui...

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Detalles Bibliográficos
Autores principales: Perry, Jeffrey W., Ahmed, Mohammad, Chang, Kyeong-Ok, Donato, Nicholas J., Showalter, Hollis D., Wobus, Christiane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390402/
https://www.ncbi.nlm.nih.gov/pubmed/22792064
http://dx.doi.org/10.1371/journal.ppat.1002783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390402/
https://www.ncbi.nlm.nih.gov/pubmed/22792064
http://dx.doi.org/10.1371/journal.ppat.1002783

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