Proteasome-Dependent Disruption of the E3 Ubiquitin Ligase Anaphase-Promoting Complex by HCMV Protein pUL21a

The anaphase-promoting complex (APC) is an E3 ubiquitin ligase which controls ubiquitination and degradation of multiple cell cycle regulatory proteins. During infection, human cytomegalovirus (HCMV), a widespread pathogen, not only phosphorylates the APC coactivator Cdh1 via the multifunctional vir...

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Detalles Bibliográficos
Autores principales: Fehr, Anthony R., Gualberto, Nathaniel C., Savaryn, John Paul, Terhune, Scott S., Yu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390409/
https://www.ncbi.nlm.nih.gov/pubmed/22792066
http://dx.doi.org/10.1371/journal.ppat.1002789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390409/
https://www.ncbi.nlm.nih.gov/pubmed/22792066
http://dx.doi.org/10.1371/journal.ppat.1002789

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