Cargando…

Proteasome-Dependent Disruption of the E3 Ubiquitin Ligase Anaphase-Promoting Complex by HCMV Protein pUL21a

The anaphase-promoting complex (APC) is an E3 ubiquitin ligase which controls ubiquitination and degradation of multiple cell cycle regulatory proteins. During infection, human cytomegalovirus (HCMV), a widespread pathogen, not only phosphorylates the APC coactivator Cdh1 via the multifunctional vir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fehr, Anthony R., Gualberto, Nathaniel C., Savaryn, John Paul, Terhune, Scott S., Yu, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390409/ https://www.ncbi.nlm.nih.gov/pubmed/22792066 http://dx.doi.org/10.1371/journal.ppat.1002789

Ejemplares similares

Identification of a short sequence in the HCMV terminase pUL56 essential for interaction with pUL89 subunit
por: Ligat, G., et al.
Publicado: (2017)

Interaction between HCMV pUL83 and human AIM2 disrupts the activation of the AIM2 inflammasome
por: Huang, Yuan, et al.
Publicado: (2017)

HCMV pUL135 Remodels the Actin Cytoskeleton to Impair Immune Recognition of Infected Cells
por: Stanton, Richard J., et al.
Publicado: (2014)

Highlighting of a LAGLIDADG and a Zing Finger Motifs Located in the pUL56 Sequence Crucial for HCMV Replication
por: Ligat, Gaëtan, et al.
Publicado: (2019)

Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex
por: Butt, Benjamin G, et al.
Publicado: (2020)

Cyclin A Degradation by Primate Cytomegalovirus Protein pUL21a Counters Its Innate Restriction of Virus Replication
por: Caffarelli, Nicolas, et al.
Publicado: (2013)

A Comparative Quantitative Proteomic Analysis of HCMV-Infected Cells Highlights pUL138 as a Multifunctional Protein
por: Li, Yang, et al.
Publicado: (2020)

N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49.5
por: Li, Chunmei, et al.
Publicado: (2023)

Dual Function of the pUL7-pUL51 Tegument Protein Complex in Herpes Simplex Virus 1 Infection
por: Albecka, Anna, et al.
Publicado: (2017)

Duck enteritis virus UL21 is a late gene encoding a protein that interacts with pUL16
por: Yang, Linjiang, et al.
Publicado: (2020)

CRISPR/Cas9 Mutagenesis of UL21 in Multiple Strains of Herpes Simplex Virus Reveals Differential Requirements for pUL21 in Viral Replication
por: Finnen, Renée L., et al.
Publicado: (2018)

New Insights into Human Cytomegalovirus pUL52 Structure
por: Muller, Clotilde, et al.
Publicado: (2021)

Distribution of the CMV glycoprotein gH/gL/gO and gH/gL/pUL128/pUL130/pUL131A complex variants and associated clinical manifestations in infants infected congenitally or postnatally
por: Paradowska, Edyta, et al.
Publicado: (2019)

pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread
por: Benedyk, Tomasz H., et al.
Publicado: (2021)

The Cytomegalovirus protein pUL37×1 targets mitochondria to mediate neuroprotection
por: Hong, Chien Tai, et al.
Publicado: (2016)

Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase
por: Casaletto, Jessica B., et al.
Publicado: (2005)

Species-Specific Inhibition of Necroptosis by HCMV UL36
por: Muscolino, Elena, et al.
Publicado: (2021)

Correction: pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread
por: Benedyk, Tomasz H., et al.
Publicado: (2022)

The herpes simplex virus tegument protein pUL21 is required for viral genome retention within capsids
por: Thomas, Ethan C. M., et al.
Publicado: (2022)

The contribution of pUL74 to growth of human cytomegalovirus is masked in the presence of RL13 and UL128 expression
por: Laib Sampaio, Kerstin, et al.
Publicado: (2016)

Human Cytomegalovirus UL29/28 Protein Interacts with Components of the NuRD Complex Which Promote Accumulation of Immediate-Early RNA
por: Terhune, Scott S., et al.
Publicado: (2010)

Expression and intracellular localization of duck enteritis virus pUL38 protein
por: Xiang, Jun, et al.
Publicado: (2010)

Variants of HCMV UL18 Sequenced Directly from Clinical Specimens Associate with Antibody and T-Cell Responses to HCMV
por: Waters, Shelley, et al.
Publicado: (2022)

Herpes simplex virus 1 protein pUL21 alters ceramide metabolism by activating the interorganelle transport protein CERT
por: Benedyk, Tomasz H., et al.
Publicado: (2022)

Human Cytomegalovirus Tegument Protein pUL71 Is Required for Efficient Virion Egress
por: Womack, Andrew, et al.
Publicado: (2010)

The Cyclin-Dependent Kinase Ortholog pUL97 of Human Cytomegalovirus Interacts with Cyclins
por: Graf, Laura, et al.
Publicado: (2013)

The Cul3–KLHL21 E3 ubiquitin ligase targets Aurora B to midzone microtubules in anaphase and is required for cytokinesis
por: Maerki, Sarah, et al.
Publicado: (2009)

The Anaphase-Promoting Complex (APC) ubiquitin ligase affects chemosensory behavior in C. elegans
por: Wang, Julia, et al.
Publicado: (2016)

Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor
por: Fletcher-Etherington, Alice, et al.
Publicado: (2020)

HECT ubiquitin ligases as accessory proteins of the plant proteasome
por: Wang, Zhishuo, et al.
Publicado: (2022)

Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells
por: Osanyinlusi, Samuel A., et al.
Publicado: (2022)

Characteristics of Immediate-Early 2 (IE2) and UL84 Proteins in UL84-Independent Strains of Human Cytomegalovirus (HCMV)
por: Manska, Salome, et al.
Publicado: (2021)

Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation
por: Häge, Sigrun, et al.
Publicado: (2021)

Human Cytomegalovirus pUL79 Is an Elongation Factor of RNA Polymerase II for Viral Gene Transcription
por: Perng, Yi-Chieh, et al.
Publicado: (2014)

The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion
por: Richards, Alexsia L., et al.
Publicado: (2017)

The Cytomegalovirus Protein Kinase pUL97: Host Interactions, Regulatory Mechanisms and Antiviral Drug Targeting
por: Steingruber, Mirjam, et al.
Publicado: (2020)

The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus
por: Häge, Sigrun, et al.
Publicado: (2021)

pUL21 regulation of pUs3 kinase activity influences the nature of nuclear envelope deformation by the HSV-2 nuclear egress complex
por: Muradov, Jamil H., et al.
Publicado: (2021)

Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch
por: Ushijima, Yoko, et al.
Publicado: (2010)

Helicase/SUMO-targeted ubiquitin ligase Uls1 interacts with the Holliday junction resolvase Yen1
por: Bauer, Stefanie L., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_n4u9qvaffsnm6m801ubuhkq53r