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Proteomic Profiling of the TRAF3 Interactome Network Reveals a New Role for the ER-to-Golgi Transport Compartments in Innate Immunity

Tumor Necrosis Factor receptor-associated factor-3 (TRAF3) is a central mediator important for inducing type I interferon (IFN) production in response to intracellular double-stranded RNA (dsRNA). Here, we report the identification of Sec16A and p115, two proteins of the ER-to-Golgi vesicular transp...

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Detalles Bibliográficos
Autores principales: van Zuylen, Wendy J., Doyon, Priscilla, Clément, Jean-François, Khan, Kashif Aziz, D'Ambrosio, Lisa M., Dô, Florence, St-Amant-Verret, Myriam, Wissanji, Tasheen, Emery, Gregory, Gingras, Anne-Claude, Meloche, Sylvain, Servant, Marc J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390413/
https://www.ncbi.nlm.nih.gov/pubmed/22792062
http://dx.doi.org/10.1371/journal.ppat.1002747