How (specific) would you like your T-cells today? Generating T-cell therapeutic function through TCR-gene transfer

T-cells are central players in the immune response against both pathogens and cancer. Their specificity is solely dictated by the T-cell receptor (TCR) they clonally express. As such, the genetic modification of T lymphocytes using pathogen- or cancer-specific TCRs represents an appealing strategy t...

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Detalles Bibliográficos
Autores principales: Daniel-Meshulam, Inbal, Ya’akobi, Shlomo, Ankri, Chen, Cohen, Cyrille J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390604/
https://www.ncbi.nlm.nih.gov/pubmed/22783259
http://dx.doi.org/10.3389/fimmu.2012.00186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390604/
https://www.ncbi.nlm.nih.gov/pubmed/22783259
http://dx.doi.org/10.3389/fimmu.2012.00186

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