Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis Are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1

Neurodegenerative diseases share two common features: enhanced oxidative stress and cellular inability to scavenge structurally damaged abnormal proteins. Pathogenesis of polyglutamine (poly(Q)) diseases involves increased protein misfolding, along with ubiquitin and chaperon protein-containing nucl...

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Detalles Bibliográficos
Autores principales: Calandria, Jorgelina M., Mukherjee, Pranab K., de Rivero Vaccari, Juan Carlos, Zhu, Min, Petasis, Nicos A., Bazan, Nicolas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Lipids
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390647/
https://www.ncbi.nlm.nih.gov/pubmed/22511762
http://dx.doi.org/10.1074/jbc.M111.287078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390647/
https://www.ncbi.nlm.nih.gov/pubmed/22511762
http://dx.doi.org/10.1074/jbc.M111.287078

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