A Conserved Motif in the C-terminal Tail of DNA Polymerase α Tethers Primase to the Eukaryotic Replisome

The DNA polymerase α-primase complex forms an essential part of the eukaryotic replisome. The catalytic subunits of primase and pol α synthesize composite RNA-DNA primers that initiate the leading and lagging DNA strands at replication forks. The physical basis and physiological significance of teth...

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Detalles Bibliográficos
Autores principales: Kilkenny, Mairi L., De Piccoli, Giacomo, Perera, Rajika L., Labib, Karim, Pellegrini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
DNA and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390648/
https://www.ncbi.nlm.nih.gov/pubmed/22593576
http://dx.doi.org/10.1074/jbc.M112.368951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390648/
https://www.ncbi.nlm.nih.gov/pubmed/22593576
http://dx.doi.org/10.1074/jbc.M112.368951

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