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Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes

AIMS/HYPOTHESIS: While genome-wide association studies (GWASs) have been successful in identifying novel variants associated with various diseases, it has been much more difficult to determine the biological mechanisms underlying these associations. Expression quantitative trait loci (eQTL) provide...

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Detalles Bibliográficos
Autores principales: Kang, H. P., Yang, X., Chen, R., Zhang, B., Corona, E., Schadt, E. E., Butte, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390705/
https://www.ncbi.nlm.nih.gov/pubmed/22584726
http://dx.doi.org/10.1007/s00125-012-2568-3