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Preparation, in vitro release, and pharmacokinetics in rabbits of lyophilized injection of sorafenib solid lipid nanoparticles

Sorafenib solid lipid nanoparticles (S-SLN) were prepared by emulsion evaporation–solidification at low temperature. Morphology was examined by transmission electron microscope. Particle size and zeta potential were determined by laser granularity equipment. Encapsulation efficiency (EE) was detecte...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Zhang, Fu-Ming, Yan, Shi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391003/
https://www.ncbi.nlm.nih.gov/pubmed/22787390
http://dx.doi.org/10.2147/IJN.S32415