High Throughput Screening for Compounds That Alter Muscle Cell Glycosylation Identifies New Role for N-Glycans in Regulating Sarcolemmal Protein Abundance and Laminin Binding

Duchenne muscular dystrophy is an X-linked disorder characterized by loss of dystrophin, a cytoskeletal protein that connects the actin cytoskeleton in skeletal muscle cells to extracellular matrix. Dystrophin binds to the cytoplasmic domain of the transmembrane glycoprotein β-dystroglycan (β-DG), w...

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Detalles Bibliográficos
Autores principales: Cabrera, Paula V., Pang, Mabel, Marshall, Jamie L., Kung, Raymond, Nelson, Stanley F., Stalnaker, Stephanie H., Wells, Lance, Crosbie-Watson, Rachelle H., Baum, Linda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391114/
https://www.ncbi.nlm.nih.gov/pubmed/22570487
http://dx.doi.org/10.1074/jbc.M111.334581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391114/
https://www.ncbi.nlm.nih.gov/pubmed/22570487
http://dx.doi.org/10.1074/jbc.M111.334581

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