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CLIPS-1D: analysis of multiple sequence alignments to deduce for residue-positions a role in catalysis, ligand-binding, or protein structure

BACKGROUND: One aim of the in silico characterization of proteins is to identify all residue-positions, which are crucial for function or structure. Several sequence-based algorithms exist, which predict functionally important sites. However, with respect to sequence information, many functionally a...

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Detalles Bibliográficos
Autores principales: Janda, Jan-Oliver, Busch, Markus, Kück, Fabian, Porfenenko, Mikhail, Merkl, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391178/
https://www.ncbi.nlm.nih.gov/pubmed/22480135
http://dx.doi.org/10.1186/1471-2105-13-55