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Prevention of methamphetamine-induced microglial cell death by TNF-α and IL-6 through activation of the JAK-STAT pathway

BACKGROUND: It is well known that methamphetamine (METH) is neurotoxic and recent studies have suggested the involvement of neuroinflammatory processes in brain dysfunction induced by misuse of this drug. Indeed, glial cells seem to be activated in response to METH, but its effects on microglial cel...

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Detalles Bibliográficos
Autores principales: Coelho-Santos, Vanessa, Gonçalves, Joana, Fontes-Ribeiro, Carlos, Silva, Ana Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391183/
https://www.ncbi.nlm.nih.gov/pubmed/22642790
http://dx.doi.org/10.1186/1742-2094-9-103