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Combinatorial Action of miRNAs Regulates Transcriptional and Post-Transcriptional Gene Silencing following in vivo PNS Injury

Injury response in the peripheral nervous system (PNS) is characterized by rapid alterations in the genetic program of Schwann cells. However, the epigenetic mechanisms modulating these changes remain elusive. Here we show that sciatic nerve injury in mice induces a cohort of 22 miRNAs, which coordi...

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Detalles Bibliográficos
Autores principales: Adilakshmi, Tadepalli, Sudol, Ida, Tapinos, Nikos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391190/
https://www.ncbi.nlm.nih.gov/pubmed/22792185
http://dx.doi.org/10.1371/journal.pone.0039674