Innate Immune Induction and Influenza Protection Elicited by a Response-Selective Agonist of Human C5a

The anaphylatoxin C5a is an especially potent mediator of both local and systemic inflammation. However, C5a also plays an essential role in mucosal host defense against bacterial, viral, and fungal infection. We have developed a response-selective agonist of human C5a, termed EP67, which retains th...

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Detalles Bibliográficos
Autores principales: Sanderson, Sam D., Thoman, Marilyn L., Kis, Kornelia, Virts, Elizabeth L., Herrera, Edgar B., Widmann, Stephanie, Sepulveda, Homero, Phillips, Joy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391237/
https://www.ncbi.nlm.nih.gov/pubmed/22792270
http://dx.doi.org/10.1371/journal.pone.0040303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391237/
https://www.ncbi.nlm.nih.gov/pubmed/22792270
http://dx.doi.org/10.1371/journal.pone.0040303

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