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Innate Immune Induction and Influenza Protection Elicited by a Response-Selective Agonist of Human C5a
The anaphylatoxin C5a is an especially potent mediator of both local and systemic inflammation. However, C5a also plays an essential role in mucosal host defense against bacterial, viral, and fungal infection. We have developed a response-selective agonist of human C5a, termed EP67, which retains th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391237/ https://www.ncbi.nlm.nih.gov/pubmed/22792270 http://dx.doi.org/10.1371/journal.pone.0040303 |