Loss of BRCA1-A Complex Function in RAP80 Null Tumor Cells

Receptor Associated Protein 80 (RAP80) is a subunit of the BRCA1-A complex and targets BRCA1 to DNA damage sites in response to DNA double strand breaks. Since mutations of BRCA1 are associated with familial ovarian cancers, we screened 26 ovarian cancer-derived cell lines for RAP80 mutations and fo...

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Detalles Bibliográficos
Autores principales: Bian, Chunjing, Wu, Rong, Cho, Kathleen, Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391255/
https://www.ncbi.nlm.nih.gov/pubmed/22792303
http://dx.doi.org/10.1371/journal.pone.0040406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391255/
https://www.ncbi.nlm.nih.gov/pubmed/22792303
http://dx.doi.org/10.1371/journal.pone.0040406

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