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Decreased Circulating C3 Levels and Mesangial C3 Deposition Predict Renal Outcome in Patients with IgA Nephropathy

BACKGROUND AND AIMS: Mesangial C3 deposition is frequently observed in patients with IgA nephropathy (IgAN). However, the role of complement in the pathogenesis or progression of IgAN is uncertain. In this observational cohort study, we aimed to identify the clinical implications of circulating C3 l...

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Detalles Bibliográficos
Autores principales: Kim, Seung Jun, Koo, Hyang Mo, Lim, Beom Jin, Oh, Hyung Jung, Yoo, Dong Eun, Shin, Dong Ho, Lee, Mi Jung, Doh, Fa Mee, Park, Jung Tak, Yoo, Tae-Hyun, Kang, Shin-Wook, Choi, Kyu Hun, Jeong, Hyeon Joo, Han, Seung Hyeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391269/
https://www.ncbi.nlm.nih.gov/pubmed/22792353
http://dx.doi.org/10.1371/journal.pone.0040495