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Autocrine Role of Angiopoietins during Megakaryocytic Differentiation

The tyrosine kinase Tie-2 and its ligands Angiopoietins (Angs) transduce critical signals for angiogenesis in endothelial cells. This receptor and Ang-1 are coexpressed in hematopoietic stem cells and in a subset of megakaryocytes, though a possible role of angiopoietins in megakaryocytic differenti...

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Detalles Bibliográficos
Autores principales: Saulle, Ernestina, Guerriero, Raffaella, Petronelli, Alessia, Coppotelli, Elena, Gabbianelli, Marco, Morsilli, Ornella, Spinello, Isabella, Pelosi, Elvira, Castelli, Germana, Testa, Ugo, Coppola, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391299/
https://www.ncbi.nlm.nih.gov/pubmed/22792187
http://dx.doi.org/10.1371/journal.pone.0039796