Transgenic IGF-IR overexpression induces mammary tumors with basal-like characteristics, whereas IGF-IR-independent mammary tumors express a claudin-low gene signature

Molecular profiling has allowed a more precise classification of human cancers. With respect to breast cancer, this approach has been used to identify five subtypes; luminal A, luminal B, HER2-enriched, basal-like and claudin-low. In addition, this approach can be used to determine the type of tumor...

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Detalles Bibliográficos
Autores principales: Franks, S E, Campbell, C I, Barnett, E F, Siwicky, M D, Livingstone, J, Cory, S, Moorehead, R A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391665/
https://www.ncbi.nlm.nih.gov/pubmed/22020329
http://dx.doi.org/10.1038/onc.2011.486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391665/
https://www.ncbi.nlm.nih.gov/pubmed/22020329
http://dx.doi.org/10.1038/onc.2011.486

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