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TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP

Epithelial-mesenchymal transition (EMT) is a crucial event in wound healing, tissue repair and cancer progression in adult tissues. We have recently shown that transforming growth factor (TGF)-β-induced EMT involves isoform switching of fibroblast growth factor receptors by alternative splicing. We...

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Detalles Bibliográficos
Autores principales: Horiguchi, K, Sakamoto, K, Koinuma, D, Semba, K, Inoue, A, Inoue, S, Fujii, H, Yamaguchi, A, Miyazawa, K, Miyazono, K, Saitoh, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391666/
https://www.ncbi.nlm.nih.gov/pubmed/22037216
http://dx.doi.org/10.1038/onc.2011.493