Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity

Membrane microvesicle shedding is an active process and occurs in viable cells with no signs of apoptosis or necrosis. We report here that microvesicles shed by oligodendroglioma cells contain an ‘aggrecanase’ activity, cleaving aggrecan at sites previously identified as targets for adamalysin metal...

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Detalles Bibliográficos
Autores principales: Lo Cicero, Alessandra, Majkowska, Iwona, Nagase, Hideaki, Di Liegro, Italia, Troeberg, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391679/
https://www.ncbi.nlm.nih.gov/pubmed/22406378
http://dx.doi.org/10.1016/j.matbio.2012.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391679/
https://www.ncbi.nlm.nih.gov/pubmed/22406378
http://dx.doi.org/10.1016/j.matbio.2012.02.005

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