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Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity
Membrane microvesicle shedding is an active process and occurs in viable cells with no signs of apoptosis or necrosis. We report here that microvesicles shed by oligodendroglioma cells contain an ‘aggrecanase’ activity, cleaving aggrecan at sites previously identified as targets for adamalysin metal...
Autores principales: | Lo Cicero, Alessandra, Majkowska, Iwona, Nagase, Hideaki, Di Liegro, Italia, Troeberg, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391679/ https://www.ncbi.nlm.nih.gov/pubmed/22406378 http://dx.doi.org/10.1016/j.matbio.2012.02.005 |
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