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The Germ Cell Determinant Blimp1 Is Not Required for Derivation of Pluripotent Stem Cells
Blimp1 (Prdm1), the key determinant of primordial germ cells (PGCs), plays a combinatorial role with Prdm14 during PGC specification from postimplantation epiblast cells. They together initiate epigenetic reprogramming in early germ cells toward an underlying pluripotent state, which is equivalent t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391686/ https://www.ncbi.nlm.nih.gov/pubmed/22770244 http://dx.doi.org/10.1016/j.stem.2012.02.023 |