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Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family

The human APOBEC3 (A3) family (A, B, C, DE, F, G, and H) comprises host defense factors that potently inhibit the replication of diverse retroviruses, retrotransposons, and the other viral pathogens. HIV-1 has a counterstrategy that includes expressing the Vif protein to abrogate A3 antiviral functi...

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Detalles Bibliográficos
Autores principales: Imahashi, Mayumi, Nakashima, Masaaki, Iwatani, Yasumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391693/
https://www.ncbi.nlm.nih.gov/pubmed/22787460
http://dx.doi.org/10.3389/fmicb.2012.00250