Basic research in HIV vaccinology is hampered by reductionist thinking

This review describes the structure-based reverse vaccinology approach aimed at developing vaccine immunogens capable of inducing antibodies that broadly neutralize HIV-1. Some basic principles of protein immunochemistry are reviewed and the implications of the extensive polyspecificity of antibodie...

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Detalles Bibliográficos
Autor principal: Van Regenmortel, Marc H. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391733/
https://www.ncbi.nlm.nih.gov/pubmed/22787464
http://dx.doi.org/10.3389/fimmu.2012.00194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391733/
https://www.ncbi.nlm.nih.gov/pubmed/22787464
http://dx.doi.org/10.3389/fimmu.2012.00194

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