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A Unique CaMKIIβ Signaling Pathway at the Centrosome Regulates Dendrite Patterning in the Brain

The protein kinase calcium/calmodulin-dependent kinase II (CaMKII) predominantly consists of the α and β isoforms in the brain. Although CaMKIIα functions have been elucidated, the unique catalytic functions of CaMKIIβ have remained unknown. Using knockdown analyses in primary neurons and in the rat...

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Detalles Bibliográficos
Autores principales: Puram, Sidharth V., Kim, Albert H., Ikeuchi, Yoshiho, Wilson-Grady, Joshua T., Merdes, Andreas, Gygi, Steven P., Bonni, Azad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391735/
https://www.ncbi.nlm.nih.gov/pubmed/21725312
http://dx.doi.org/10.1038/nn.2857