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Integrating Genome and Functional Genomics Data to Reveal Perturbed Signaling Pathways in Ovarian Cancers

Cancers are genetic diseases, driven by somatic mutations that perturb cellular signaling systems. In this study, we aim to reveal the signal transduction pathways that are perturbed by mutations in ovarian cancer. Our approach searches for genetic mutations that lead to a common cellular response,...

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Detalles Bibliográficos
Autores principales: Lu, Songjian, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392049/
https://www.ncbi.nlm.nih.gov/pubmed/22779056