Reticulon-like-1, the Drosophila orthologue of the Hereditary Spastic Paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons

Several causative genes for hereditary spastic paraplegia encode proteins with intramembrane hairpin loops that contribute to the curvature of the endoplasmic reticulum (ER), but the relevance of this function to axonal degeneration is not understood. One of these genes is reticulon2. In contrast to...

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Detalles Bibliográficos
Autores principales: O'Sullivan, Niamh C., Jahn, Thomas R., Reid, Evan, O'Kane, Cahir J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392112/
https://www.ncbi.nlm.nih.gov/pubmed/22543973
http://dx.doi.org/10.1093/hmg/dds167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392112/
https://www.ncbi.nlm.nih.gov/pubmed/22543973
http://dx.doi.org/10.1093/hmg/dds167

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