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Formulation, characterization, and evaluation of in vitro skin permeation and in vivo pharmacodynamics of surface-charged tripterine-loaded nanostructured lipid carriers

BACKGROUND: Nanostructured lipid carriers (NLCs) are attractive materials for topical drug delivery, and in a previous study, we demonstrated that NLCs loaded with tripterine enhance its deposition. However, the surface charge of nanoparticles influences percutaneous drug penetration. Therefore, we...

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Detalles Bibliográficos
Autores principales:	Chen, Yan, Zhou, Lei, Yuan, Ling, Zhang, Zhen-hai, Liu, Xuan, Wu, Qingqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392146/ https://www.ncbi.nlm.nih.gov/pubmed/22787398 http://dx.doi.org/10.2147/IJN.S32476

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