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A Study on the Effect of Surface Lysine to Arginine Mutagenesis on Protein Stability and Structure Using Green Fluorescent Protein

Two positively charged basic amino acids, arginine and lysine, are mostly exposed to protein surface, and play important roles in protein stability by forming electrostatic interactions. In particular, the guanidinium group of arginine allows interactions in three possible directions, which enables...

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Detalles Bibliográficos
Autores principales: Sokalingam, Sriram, Raghunathan, Govindan, Soundrarajan, Nagasundarapandian, Lee, Sun-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392243/
https://www.ncbi.nlm.nih.gov/pubmed/22792305
http://dx.doi.org/10.1371/journal.pone.0040410