Cargando…
A Study on the Effect of Surface Lysine to Arginine Mutagenesis on Protein Stability and Structure Using Green Fluorescent Protein
Two positively charged basic amino acids, arginine and lysine, are mostly exposed to protein surface, and play important roles in protein stability by forming electrostatic interactions. In particular, the guanidinium group of arginine allows interactions in three possible directions, which enables...
Autores principales: | Sokalingam, Sriram, Raghunathan, Govindan, Soundrarajan, Nagasundarapandian, Lee, Sun-Gu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392243/ https://www.ncbi.nlm.nih.gov/pubmed/22792305 http://dx.doi.org/10.1371/journal.pone.0040410 |
Ejemplares similares
-
Deletional Protein Engineering Based on Stable Fold
por: Raghunathan, Govindan, et al.
Publicado: (2012) -
Conjugation of Proteins by Installing BIO-Orthogonally Reactive Groups at Their N-Termini
por: Soundrarajan, Nagasundarapandian, et al.
Publicado: (2012) -
Green fluorescent protein as a scaffold for high efficiency production of functional bacteriotoxic proteins in Escherichia coli
por: Soundrarajan, Nagasundarapandian, et al.
Publicado: (2016) -
A variant of green fluorescent protein exclusively deposited to active intracellular inclusion bodies
por: Raghunathan, Govindan, et al.
Publicado: (2014) -
Protegrin-1 cytotoxicity towards mammalian cells positively correlates with the magnitude of conformational changes of the unfolded form upon cell interaction
por: Soundrarajan, Nagasundarapandian, et al.
Publicado: (2019)