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Cooperative Interaction between the MUC1-C Oncoprotein and the Rab31 GTPase in Estrogen Receptor-Positive Breast Cancer Cells

Rab31 is a member of the Ras superfamily of small GTPases that has been linked to poor outcomes in patients with breast cancer. The MUC1-C oncoprotein is aberrantly overexpressed in most human breast cancers and also confers a poor prognosis. The present results demonstrate that MUC1-C induces Rab31...

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Detalles Bibliográficos
Autores principales: Jin, Caining, Rajabi, Hasan, Pitroda, Sean, Li, Ailing, Kharbanda, Akriti, Weichselbaum, Ralph, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392244/
https://www.ncbi.nlm.nih.gov/pubmed/22792175
http://dx.doi.org/10.1371/journal.pone.0039432