Cargando…

Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells

Resistance to chemotherapy is a major obstacle for the effective treatment of cancers. Lin28 has been shown to contribute to tumor relapse after chemotherapy; however, the relationship between Lin28 and chemoresistance remained unknown. In this study, we investigated the association of Lin28 with pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Kezhen, Liu, Liqun, Wang, Linbo, Yu, Jiren, Liu, Xiaojiao, Cheng, Yongxia, Dong, Minjun, Teng, Rongyue, Wu, Linjiao, Fu, Peifen, Deng, Wuguo, Hu, Wenxian, Teng, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392258/
https://www.ncbi.nlm.nih.gov/pubmed/22808086
http://dx.doi.org/10.1371/journal.pone.0040008