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Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis

INTRODUCTION: A subgroup of voltage gated sodium channels including Nav1.8 are exclusively expressed on small diameter primary afferent neurons and are therefore believed to be integral to the neurotransmission of nociceptive pain. The present study examined whether local application of A-803467, a...

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Detalles Bibliográficos
Autores principales: Schuelert, Niklas, McDougall, Jason J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392791/
https://www.ncbi.nlm.nih.gov/pubmed/22225591
http://dx.doi.org/10.1186/ar3553