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Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies

INTRODUCTION: Autoreactivity to histones is a pervasive feature of several human autoimmune disorders, including systemic lupus erythematosus (SLE). Specific post-translational modifications (PTMs) of histones within neutrophil extracellular traps (NETs) may potentially drive the process by which to...

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Detalles Bibliográficos
Autores principales:	Liu, Chih Long, Tangsombatvisit, Stephanie, Rosenberg, Jacob M, Mandelbaum, Gil, Gillespie, Emily C, Gozani, Or P, Alizadeh, Ash A, Utz, Paul J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392818/ https://www.ncbi.nlm.nih.gov/pubmed/22300536 http://dx.doi.org/10.1186/ar3707

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